Emerging antibody products and Nicotiana manufacturing.

نویسندگان

  • Kevin J Whaley
  • Andrew Hiatt
  • Larry Zeitlin
چکیده

Antibody based products are not widely available to address multiple global health challenges due to high costs, limited manufacturing capacity, and long manufacturing lead times. Nicotiana-based manufacturing of antibody products may now begin to address these challenges as a result of revolutionary advances in transient expression and altered glycosylation pathways. This review provides examples of emerging antibody-based products (mucosal and systemic) that could be competitive and commercially viable when the attributes of Nicotiana-based manufacturing (large scale, versatile, rapid, low cost) are utilized.

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عنوان ژورنال:
  • Human vaccines

دوره 7 3  شماره 

صفحات  -

تاریخ انتشار 2011